Lose Body Fat

The Science Behind Fat Loss

Losing body fat requires understanding the processes your body uses to burn fat and create an energy deficit. By knowing how fat loss works, you can make informed choices that support long-term success.

How the Body Burns Fat

The process of fat burning, or lipolysis, occurs when the body breaks down stored fat to release fatty acids, which are then used as fuel. This process involves several steps:

  1. Lipolysis: Stored fat molecules are broken down into fatty acids and glycerol.
  2. Oxidation: Fatty acids are transported to the mitochondria in cells, where they are converted to energy (Schmidt et al., 2021; Alkahtani, 2014).³,⁴

Hormones, including adrenaline and cortisol, can trigger fat release, especially during physical activity or periods of caloric deficit. By incorporating regular exercise and achieving a caloric deficit, you can promote consistent fat burning.

Importance of Metabolism and Caloric Deficit

Achieving a caloric deficit is essential for fat loss—meaning you burn more calories than you consume. Metabolism plays a key role in determining daily calorie expenditure and is composed of:

  1. Basal Metabolic Rate (BMR): The calories burned at rest to maintain essential bodily functions.
  2. Thermic Effect of Food (TEF): Calories burned during digestion and absorption of food.
  3. Physical Activity: Calories burned during exercise and daily movements.

While reducing calorie intake helps create a deficit, overly restrictive dieting can lead to metabolic adaptation, where the body conserves energy to protect against weight loss. To maintain a healthy metabolism, it’s essential to focus on gradual calorie reduction and include resistance training, which helps preserve muscle mass and metabolic rate (Melanson et al., 2009; Miller et al., 2022).⁵,⁶

Category: Lose Body Fat

  1. Licher S, Heshmatollah A, van der Willik KD, et al. Life Expectancy and Years Lived With and Without Alzheimer’s Disease. JAMA Neurol. 2020;77(11):1438-1446. doi:10.1001/jamaneurol.2020.3024
  2. Parmenter BH, Dieberg G, Smart NA. Exercise training for management of peripheral arterial disease: a systematic review and meta-analysis. Sports Med. 2015;45(2):231-244. doi:10.1007/s40279-014-0276-2
  3. Schmidt RL, Agrawal R, Bakhtina K, et al. Caffeine enhances the thermogenic response to ingested glucose. Nutrients. 2021;13(9):3148. doi:10.3390/nu13093148.
  4. Alkahtani SA. Comparing fat oxidation in an exercise test with moderate-intensity interval training. J Sports Sci Med. 2014;13(1):51-58.
  5. Melanson EL, MacLean PS, Hill JO. Exercise improves fat metabolism in muscle but does not increase 24-h fat oxidation. Exerc Sport Sci Rev. 2009;37(2):93-101. doi:10.1097/JES.0b013e31819c2f2e.
  6. Miller T, Mason N, Johnston N, et al. Long-term dietary adherence and its relationship with weight loss in the context of an intermittent fasting dietary pattern: a randomized controlled trial. Obesity (Silver Spring). 2022;30(8):1696-1705. doi:10.1002/oby.23517.
  7. Linardon J, Messer M. Meta-analysis of the effects of intermittent fasting on weight loss and metabolic function. Nutrients. 2021;13(9):3183. doi:10.3390/nu13093183.
  8. Benardot D. Advanced sports nutrition. 2nd ed. Champaign, IL: Human Kinetics; 2012.
  9. Naimi TS, Brewer RD, Mokdad A, et al. Binge drinking among US adults. JAMA. 2003;289(1):70-75. doi:10.1001/jama.289.1.70.
  10. Dulloo AG, Jacquet J, Montani JP. Pathways from weight fluctuations to metabolic diseases: focus on maladaptive thermogenesis during catch-up fat. Int J Obes (Lond). 2012;36(11):1420-1432. doi:10.1038/ijo.2011.278.
  11. Trexler ET, Smith-Ryan AE, Norton LE. Metabolic adaptation to weight loss: implications for the athlete. J Int Soc Sports Nutr. 2014;11:7. doi:10.1186/1550-2783-11-7.
  12. Slentz CA, Bateman LA, Willis LH, et al. Effects of exercise training intensity on abdominal visceral fat and body composition. Med Sci Sports Exerc. 2011;43(11):1863-1873. doi:10.1249/MSS.0b013e3181d83a64.
  13. Melby CL, Paris HL, Foright RM, Peth J. Attenuating the biologic drive for weight regain following weight loss: must what goes down always go back up? Nutrients. 2017;9(5):468. doi:10.3390/nu9050468.
  14. Schoenfeld BJ, Grgic J, Ogborn D, Krieger JW. Strength and hypertrophy adaptations between low- vs. high-load resistance training: a systematic review and meta-analysis. J Strength Cond Res. 2017;31(12):3508-3523. doi:10.1519/JSC.0000000000002200.
  15. Mazure CM, Jones DP. Twenty years and still counting: including women as participants and studying sex and gender in biomedical research. BMC Womens Health. 2015;15:94. doi:10.1186/s12905-015-0251-9.
  16. Karl JP, Margolis LM, Madslien EH, Murphy NE, Castellani JW, Lieberman HR. Changes in intestinal microbiota composition and metabolism coincide with increased intestinal permeability in young adults under prolonged physiologic stress. Am J Physiol Gastrointest Liver Physiol. 2017;312(6)
    . doi:10.1152/ajpgi.00066.2017.
  17. Schoenfeld BJ, Aragon AA, Krieger J. Effects of meal frequency on weight loss and body composition: a meta-analysis. Nutr Rev. 2015;73(2):69-82. doi:10.1093/nutrit/nuu017.
  18. Kim JE, O’Connor LE, Sands LP, Slebodnik MB, Campbell WW. Effects of dietary protein intake on body composition changes after weight loss in older adults: a systematic review and meta-analysis. Nutr Rev. 2016;74(3):210-224. doi:10.1093/nutrit/nuv065.
  19. LeCheminant JD, Hinman T, Pratt KB, Fernhall B. Exercise and body fat composition in children: a meta-analysis of randomized controlled trials. J Pediatr. 2009;155(5):611-618. doi:10.1016/j.jpeds.2009.04.002.
  20. Wilson JM, Lowery RP, Roberts MD, Sharp MH, Joy JM. The effects of intermittent fasting on metabolic health: an evidence-based review. J Int Soc Sports Nutr. 2015;12:47. doi:10.1186/s12970-015-0108-9.
  21. Esposito K, Chiodini P, Capuano A, et al. Colorectal cancer risk in patients with type 2 diabetes with or without insulin therapy: a systematic review and meta-analysis of observational studies. Diabetes Care. 2012;35(12):2458-2465. doi:10.2337/dc12-0715.
  22. Bird SP, Tarpenning KM, Marino FE. Effects of aerobic and resistance exercise on circulating hormone concentrations in middle-aged and older men. Gerontology. 2009;55(6):627-633. doi:10.1159/000230465.
  23. Caspersen CJ, Powell KE, Christenson GM. Physical activity, exercise, and physical fitness: definitions and distinctions for health-related research. Public Health Rep. 1985;100(2):126-131.

Fat Loss Supplements

Fat Loss Articles